Prevalence and Associated Factors of Depressive Disorders in Patients with Acute Coronary Syndrome

Abstract

ABSTRACT
Objective : To determine the prevalence and associated factors of depressive disorder in patients with acute coronary syndrome (ACS) hospitalized in Siriraj Hospital.
Method : A descriptive cross-sectional study was conducted. Participants were 124 patients with ACS who were admitted to the CCU and ICCU Siriraj Hospital during August 2010 - March 2011. Information was collected using case record forms for baseline characteristics. Depressive disorders were assessed by investigators using M.I.N.I. (Mini international neuropsychiatric interview) modules for major depressive episode, dysthymia, suicidality and hamilton rating scale for depression (Thai version) (HAM-D) using out off point above 7.
Results : The prevalence of depressive disorder in patients with ACS was 14.5%. In stepwises logistic regression analysis, factors associated with depressive disorders were previous ACS (adjusted OR 3.37, 95%CI 1.005-11.285, p=0.049), history of
psychiatric diseases (adjusted OR 14.77, 95%CI 1.702-128.088, p=0.015), financial problems (adjusted OR 5.11, 95%CI 1.47-17.772, p=0.01) and current sedative-hypnotic drugs use (adjusted OR 11.79, 95%CI 2.7-51.47, p=0.001).
Conclusion : The prevalence of depressive disorder in patients with ACS was high. Factors associated with depressive disorders were previous ACS, history of psychiatric diseases, financial problems and current sedative-hypnotic drugs use.